Portfolio and Platform Lead, Accelerator

Tags: Global Health Environment
  • Added Date: Friday, 19 December 2025
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The Foundation

We are the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees should reflect the rich diversity of the global populations we aim to serve. We provide an exceptional benefits package to employees and their families which include comprehensive medical, dental, and vision coverage with no premiums, generous paid time off, paid family leave, foundation-paid retirement contribution, regional holidays, and opportunities to engage in several employee communities. As a workplace, weโ€™re committed to creating an environment for you to thrive both personally and professionally.

The TeamOur Global Health (GH) program harnesses advances in science and technology to save lives in low and middle income countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where proven tools exist, we support sustainable ways to improve their delivery. Where they donโ€™t, we invest in research and development of new interventions, such as vaccines, drugs, and diagnostics. Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis, neglected and other infectious diseases, enteric and diarrheal diseases and pneumonia. These strategies are supported by functional teams that focus on Discovery and Translational Sciences, Vaccine Development, and Integrated Development.

The Accelerator funds the creation of novel technology capabilities that enable the achievement of the foundationโ€™s mission by fostering the conception, design, and testing of fundamentally new biotech platforms that have the potential to change current best practices or business models and show proof of concept for these platforms. By leveraging grants, equity, and donor capital, we work to ensure the capabilities advanced further the foundationโ€™s objectives and support the transition of these new technology platforms to execution partners. Some platform capabilities that we are exploring include harnessing the power of chemo-sensing for ultra-high sensitivity detection of volatiles, programming immune system responses for design of next generation vaccine modalities, and engineering antibodies for oral delivery. We will be exploring exciting new transformative technology capabilities beyond these within our broad mandate. Our team also includes more mature programmatic units aiming to achieve a โ€œsingle-shot cureโ€ for HIV and sickle cell disease in the next ten years, harness AI and machine learning tools to radically advance drug discovery and development to cure HPV and pre-eclampsia, and develop five new preclinical oral polio vaccine candidates in the next two years.

Your Role

We are currently seeking a Portfolio and Platform Lead (PPL) for the Accelerator team within the Global Health Division. The candidate will help put together and apply integrated product development plans, as well as bring deep platform implementation and management experience to the Accelerator portfolio. The PPL will apply relevant technical and execution expertise to best suit the complex ecosystem in which Global Health works with various partners (academic institutions, biotechs, PDPs, Pharma). The candidate will work with the Accelerator team and its partners to ensure that: (a) the portfolio of investments related to product development have robust implementation plans that ultimately result in effective, impactful, deliverable interventions; and (b) the portfolio of investments in cross-cutting platforms have robust development, implementation and tracking plans that facilitate the de-risking, advancement and/or termination of product/intervention concepts and candidates in a rational, expedited manner. The PPL will leverage subject matter and execution expertise relevant to drugs, vaccines, biologics, and novel technological platforms, and apply rigorous methodology to assist the Accelerator in assessing, managing, and continuously refining the portfolios to achieve optimal global health impact through our partners and grantees. The Accelerator works predominantly in preclinical innovation for fundamentally new modalities, requiring expertise and comfort in development of novel clinical products.

What Youโ€™ll Do

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